FIRST GENERATION CALCIUM CHANNEL ANTAGONISTS
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1: OBJECTIVES
2: OF PILLS AND POTIONS
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13: INTRACELLULAR Ca++ FUNCTIONS
14: Calcium Balance Chart
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17: Cell Structure Chart
18: PROPOSED THAT TWO CALCIUM CHANNELS EXIST
19: RECEPTOR OPERATED CHANNEL
20: VOLTAGE SENSITIVE CHANNEL
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23: CALCIUM CHANNEL ANTAGONISTS
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30: FIRST GENERATION CALCIUM CHANNEL ANTAGONISTS
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36: SECOND GENERATION AGENTS
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38: CONGESTIVE HEART FAILURE
39: SECOND GENERATION CALCIUM CHANNEL ANTAGONISTS
40: SECOND GENERATION AGENTS
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47: TIGHT HYPERTENSIVE CONTROL
48: TIGHT HYPERTENSIVE CONTROL
49: THREE STUDIES REPORTING INCREASED RISK WITH ANTIHYPERTENSIVE DRUGS
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55: DRUGS METABOLIZED BY CYP 3A3/4
56: DRUGS INHIBITING
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58: CALCIUM CHANNEL ANTAGONISTS
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61: L-type Channel Model
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66: Calcium Balance Chart
67: Calcium Balance Chart
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71: SECOND GENERATION AGENTS
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75: FIRST GENERATION AGENTS
